Peer-reviewed veterinary case report
Treatment of canine lymphosarcoma with carmustine, vincristine
By Ricci Lucas, Sílvia Regina et al.·Published in Journal of the American Animal Hospital Association·2004·Faculdade de Medicina, Brazil·View original on PubMed →
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Original publication title: Carmustine, vincristine, and prednisone in the treatment of canine lymphosarcoma.
- Species:
- dog
Plain-English summary
A group of dogs with multicentric malignant lymphosarcoma (a type of cancer) was treated with a combination of carmustine, vincristine, and prednisone. Out of seven dogs, six went into complete remission, meaning their cancer was no longer detectable, while one dog showed a partial response. On average, the dogs lived about 386 days after starting treatment, with remission lasting around 323 days. The treatment was generally well-tolerated, with no major side effects affecting blood counts or liver function. This suggests that carmustine can be an effective option for treating this type of cancer in dogs.
People also search for: dog lymphosarcoma treatment · canine cancer chemotherapy · carmustine for dogs · dog cancer remission time
Abstract
A chemotherapeutic protocol using carmustine in combination with vincristine and prednisone was tested in dogs with multicentric malignant lymphosarcoma. Of seven dogs treated, six (85.7%) achieved complete remission. A partial response occurred in one dog. Median survival time was 224 days (mean 386 days), and median duration of remission was 183 days (mean 323 days). Marked neutropenia was observed following carmustine administration. There were no significant alterations in platelets and red blood cell counts during treatment, and no abnormalities attributable to the chemotherapy were found in serum biochemical profiles. Results of this study showed that carmustine is an effective alternative option in the treatment of canine lymphosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15238559/