Peer-reviewed veterinary case report
Blood type and breed risks for immune anemia in dogs
By Miller, Sybille A et al.·Published in Journal of the American Veterinary Medical Association·2004·The Department of Medicine, United States·View original on PubMed →
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Original publication title: Case-control study of blood type, breed, sex, and bacteremia in dogs with immune-mediated hemolytic anemia.
- Species:
- dog
Plain-English summary
A study looked at 33 dogs with immune-mediated hemolytic anemia (IMHA), a condition where the immune system attacks red blood cells, to see if blood type, breed, or sex affected their risk. It found that certain breeds like Cocker Spaniels and Bichon Frise were more likely to develop IMHA, and female dogs had a higher risk as well. Interestingly, none of the dogs tested for bacterial infections had any signs of bacteremia (blood infection). This information can help veterinarians understand which dogs might be more susceptible to this serious condition.
People also search for: dog IMHA symptoms · Cocker Spaniel blood type risk · female dog anemia treatment
Abstract
OBJECTIVE: To determine whether blood type, breed, or sex were risk factors for immune-mediated hemolytic anemia (IMHA) in dogs and whether bacteremia was common in dogs with IMHA. DESIGN: Case-control study. ANIMALS: 33 dogs with IMHA, 1,014 dogs without IMHA for which blood type (dog erythrocyte antigens 1.1, 1.2, 3, 4, 5, and 7) was known, 15,668 dogs without IMHA for which breed was known, and 15,589 dogs without IMHA for which sex was known. PROCEDURE: Blood type, breed, and sex distribution of dogs with IMHA were compared with data for control dogs with Fisher exact tests and by calculating odds ratios (ORs). Results of bacterial culture of blood samples were documented for dogs with IMHA, when available. RESULTS: Dog erythrocyte antigen 7 was associated with a significant protective effect (OR, 0.1) in Cocker Spaniels with IMHA (n = 10), compared with control dogs. Cocker Spaniels, Bichon Frise, Miniature Pinschers, Rough-coated Collies, and Finnish Spitz had a significantly increased risk of IMHA, as did female dogs (OR, 2.1). Blood samples from 12 dogs with IMHA were submitted for bacterial culture, and none had bacteremia. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that blood type, breed, and sex may play a role in IMHA in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14736067/