Peer-reviewed veterinary case report
Dog with amyloid-producing jaw tumor that spread to lungs years later
By Blackford Winders, Callie et al.Ā·Published in Frontiers in veterinary scienceĀ·2020Ā·College of Veterinary Medicine, United StatesĀ·View original on PubMed ā
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Original publication title: Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano-Proof of Malignant Potential.
- Species:
- dog
Plain-English summary
A 1-year-old male Spinone Italiano was treated for a tumor in his mouth called an amyloid-producing odontogenic tumor. After surgery and radiation, he seemed fine for six years, but then a new mass appeared on his jaw along with a nodule in his lung. Tests showed that both the new jaw mass and the lung nodule were also amyloid-producing odontogenic tumors. This case highlights that these tumors can spread and occur in different areas of the body over time.
People also search for: Spinone Italiano mouth tumor Ā· dog lung nodule treatment Ā· amyloid tumor in dogs
Abstract
A 1-year-old male Spinone Italiano dog was treated for an amyloid-producing odontogenic tumor on the right maxilla with a cytoreductive surgery followed by a definitive radiation protocol. Six years later, the dog presented for a new mass on the rostral mandible as well as a lung nodule without recurrence of the original maxillary tumor. Both the mandibular mass and the lung nodule were histologically confirmed to be amyloid-producing odontogenic tumor based on the appearance of sheets and cords of the odontogenic epithelium disrupted by amorphous extracellular amyloid. This case illustrates the metastatic potential for amyloid-producing odontogenic tumor in dogs and asynchronous occurrence of multiple APOTs in the oral cavity.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33134357/