Peer-reviewed veterinary case report
Dog with amyloid-producing jaw tumor that spread to lungs
By Callie Blackford Winders et al.·Published in Frontiers in Veterinary Science·2020·College of Veterinary Medicine, University of Minnesota, St. Paul, MN, United States, CH·View original on DOAJ →
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Original publication title: Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential
- Species:
- dog
Plain-English summary
A 1-year-old male Spinone Italiano was treated for a tumor in his mouth that produced amyloid, a type of protein. After surgery and radiation, he seemed fine for six years, but then a new mass appeared on his jaw along with a nodule in his lung. Tests confirmed that both the new mass and lung nodule were also amyloid-producing tumors. This case highlights that these tumors can spread and appear in different areas of the body over time.
People also search for: Spinone Italiano mouth tumor · dog lung nodule treatment · amyloid tumor in dogs
Abstract
A 1-year-old male Spinone Italiano dog was treated for an amyloid-producing odontogenic tumor on the right maxilla with a cytoreductive surgery followed by a definitive radiation protocol. Six years later, the dog presented for a new mass on the rostral mandible as well as a lung nodule without recurrence of the original maxillary tumor. Both the mandibular mass and the lung nodule were histologically confirmed to be amyloid-producing odontogenic tumor based on the appearance of sheets and cords of the odontogenic epithelium disrupted by amorphous extracellular amyloid. This case illustrates the metastatic potential for amyloid-producing odontogenic tumor in dogs and asynchronous occurrence of multiple APOTs in the oral cavity.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3389/fvets.2020.576376