Peer-reviewed veterinary case report
Nasal discharge with brain transferrin in a dog with seizures
By Kosuke Kinoshita et al.·Published in Frontiers in Veterinary Science·2022·Veterinary Medical Center, Osaka Prefecture University, Izumisano, Japan, CH·View original on DOAJ →
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Original publication title: Case Report: Detection of Transferrin in a Dog Suspected of Having Cerebrospinal Fluid Rhinorrhea
- Species:
- dog
Plain-English summary
A 12-year-old Yorkshire terrier was brought to the vet because he was having seizures and had a clear, watery discharge from his nose. The vet suspected a condition called cerebrospinal fluid rhinorrhea, where fluid from the brain leaks into the nasal passages. Tests showed that the nasal discharge contained glucose and a specific protein called brain-type transferrin, which can help confirm this diagnosis. While the dog was diagnosed with this condition, the abstract does not specify the treatment or outcome.
People also search for: dog seizures and nasal discharge · cerebrospinal fluid rhinorrhea in dogs · Yorkshire terrier seizure treatment
Abstract
A 12-year-old Yorkshire terrier was referred for epileptic seizures and nasal discharge. The fluid was clear and serous. Cerebrospinal fluid (CSF) rhinorrhea was suspected, based on clinical signs and MRI findings. In humans, analysis of nasal secretions to determine the concentration of glucose and brain-type transferrin has been widely used clinically in order to confirm the presence of CSF rhinorrhea. The glucose concentration in the nasal discharge was 74 mg/dL. Serum-type and brain-type isoforms of transferrin were detectable in the nasal sample. The concentration of glucose and brain-type transferrin could be useful for diagnosing CSF rhinorrhea.
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Search related cases →Original publication on DOAJ: https://doi.org/10.3389/fvets.2022.845809