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Peer-reviewed veterinary case report

Cat with heart failure diagnosed with cardiac lymphoma after death

By Jake Johnson et al.·Published in Frontiers in Veterinary Science·2024·View original on DOAJ

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Original publication title: Case report: Diffuse large B-cell lymphoma presenting as congestive heart failure in a cat

Species:
cat

Plain-English summary

A 10-year-old male domestic short-haired cat was experiencing congestive heart failure and had a history of feline immunodeficiency virus and diabetes. Unfortunately, the cat was humanely euthanized, and a post-mortem examination revealed that the heart was affected by a type of cancer called diffuse large B-cell lymphoma. This rare form of cardiac lymphoma can sometimes be overlooked in cats with heart issues. The findings suggest that the cat's chronic viral infection may have played a role in the development of this cancer.

People also search for: cat congestive heart failure symptoms · feline lymphoma treatment · cat heart disease and diabetes

Abstract

Cardiac lymphoma is uncommon in cats and is rarely considered as a differential diagnosis for congestive heart failure. A 10-year-old neutered male domestic short-haired cat with clinical histories of feline immunodeficiency virus, diabetes mellitus, and congestive heart failure was humanely euthanized. Post-mortem evaluation demonstrated a massively infiltrative round cell neoplasm of the heart, resulting in CHF. Immunohistochemistry of neoplastic tissue was consistent with diffuse large B-cell lymphoma. This case demonstrates a peculiar presentation of cardiac diffuse large B-cell lymphoma, with chronic feline lentiviral infection possibly contributing to disease initiation and progression.

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Original publication on DOAJ: https://doi.org/10.3389/fvets.2024.1467448