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Peer-reviewed veterinary case report

Axillary lump diagnosed as neuroblastoma-like schwannoma in cat

By Chen, Vivian S et al.·Published in Frontiers in veterinary science·2022·Charles River Laboratories, United States·View original on PubMed

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Original publication title: Case Report: Neuroblastoma-Like Schwannoma in a Domestic Short-Haired Cat.

Species:
cat

Plain-English summary

A 6-year-old male domestic short-haired cat had a lump found in his armpit during a routine check-up. After surgery to remove the mass, it was identified as a rare type of tumor called a neuroblastoma-like schwannoma, which is generally benign. The mass was firm and white, measuring about half a centimeter across. Fortunately, the cat recovered well after the surgery, and there were no signs of further issues.

People also search for: cat lump under armpit · cat tumor surgery recovery · domestic short-haired cat mass

Abstract

An axillary mass was detected in a 6-year-old, neutered, male, domestic short-haired cat during a wellness exam. Gross examination following surgical removal revealed a discrete, deep subcutaneous, discoid mass that was between 0.5- and 0.7-cm-in-diameter and diffusely firm and white. Histologically, the mass was well-demarcated, partially encapsulated, and expanded the panniculus carnosus. It was composed of tightly packed, giant rosettes of radially arranged fusiform cells stacked in one to 10 layers with peripherally palisading nuclei and with centrally oriented, fibrillary, cytoplasmic processes, and collagenous fibers. Laminin immunoreactivity and ultrastructural examination highlighted a continuous basal lamina outside the plasma membrane of each neoplastic cell. Neoplastic cells were immunoreactive for GFAP, S100, periaxin, and Sox-10 and were immunonegative for synaptophysin, smooth muscle actin, and pancytokeratin. Collective findings were consistent with a diagnosis of neuroblastoma-like schwannoma. This is the first veterinary report of this rare variant of benign schwannoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35782550/