Peer-reviewed veterinary case report
Dog with nerve tumor invading skull and brain causing balance problems
By Hidari, Kyosuke et al.·Published in Frontiers in veterinary science·2022·Neuro Vets Animal Neurology Clinic, Japan·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Case report: Presumptive subcutaneous malignant peripheral nerve sheath tumor with intracranial invasion and osteolysis in the posterior fossa of a dog.
- Species:
- dog
Plain-English summary
A 13-year-old male Toy Poodle was brought to the vet with sudden balance issues, which can indicate a vestibular disorder. Imaging tests showed a large mass in the dog's skull that was damaging the bone and affecting the brain area. A biopsy revealed that the mass was likely a malignant peripheral nerve sheath tumor, a type of cancer that can be aggressive. Unfortunately, due to the tumor's severity and location, treatment options may be limited, and the prognosis can be poor.
People also search for: dog balance problems · Toy Poodle tumor symptoms · malignant peripheral nerve sheath tumor in dogs
Abstract
A 13-year-old castrated male Toy Poodle presented with an acute vestibular disorder. Magnetic resonance imaging and computed tomography revealed a large oval space-occupying mass with skull destruction located from the subcutaneous tissue to the posterior fossa region. Histopathologically, the mass was a bundled growth of spindle-shaped mesenchymal tumor cells between the myofibrillar and collagen bundles. The cells were moderately irregular in size and had eosinophilic stained cytoplasm. The cells were highly atypical and had rare mitotic figures. Neoplastic cells were immunoreactive for S100, GFAP, Olig-2, SOX10 and immunonegative for NF, E-cadherin, and Claudin-1. Collective findings were presumptive with a diagnosis of malignant peripheral nerve sheath tumor.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36425125/