Peer-reviewed veterinary case report
Cats catch H3 flu viruses more easily than dogs
By Deng, Jie et al.·Published in Virulence·2026·College of Veterinary Medicine, China·View original on PubMed →
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Original publication title: Cats are more susceptible to the prevalent H3 subtype influenza viruses than dogs.
- Species:
- dog
Plain-English summary
A group of cats was tested for their response to three types of H3 influenza viruses, while dogs were also included in the study for comparison. Although both species showed signs of exposure to the viruses, the cats had a more severe reaction, with nasal shedding of the virus and replication in their lungs, while the dogs showed no clinical signs or viral shedding. This study highlights that cats are more susceptible to these influenza viruses than dogs, which could be important for pet owners to know. Increased monitoring of cats for influenza is recommended to prevent potential outbreaks.
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Abstract
Recent reports have highlighted the increasing frequency of influenza A virus (IAV) spillover events from other species to dogs and cats. IAV, particularly the H3 subtype, exhibits a broad host range and a propensity for interspecies transmission, as exemplified by the sustained circulation of H3N2 and H3N8 canine influenza viruses in dog populations. This raises concerns about the potential role of companion animals as intermediate hosts in influenza virus transmission. To evaluate the susceptibility of dogs and cats to the prevalent H3 subtype influenza viruses, we experimentally inoculated groups of both species with three prevalent influenza viruses: H3N2 avian influenza virus (AIV), H3N8 avian influenza virus, and H3N2 swine influenza virus (SIV). Results showed that while all inoculated dogs exhibited seroconversion to all three viruses at 7, 14, and 21 days post-inoculation (dpi), they displayed no clinical signs, viral shedding, or evidence of viral replication in their organ tissues. In contrast, despite the cats did not exhibit apparent clinical signs, all inoculated cats exhibited seroconversion to all viruses at 7, 14 and 21 dpi, sustained nasal viral shedding for approximately one week, and demonstrated viral replication in their lungs, trachea, and nasal turbinate. Our findings underscore the higher susceptibility of cats compared to dogs to H3 subtype influenza viruses. These results emphasize the critical need for enhanced surveillance of cats within the influenza virus transmission network.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41408147/