Peer-reviewed veterinary case report
Dog develops diabetes insipidus after heart arrest and recovers
By Bellis, Tara et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2015·From BluePearl Veterinary Specialists, United States·View original on PubMed →
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Original publication title: Central diabetes insipidus following cardiopulmonary arrest in a dog.
- Species:
- dog
Plain-English summary
An 8-week-old puppy was brought in for emergency care after experiencing a cardiac arrest. After being resuscitated, the puppy showed signs of neurological issues and developed excessive urination and dilute urine. The veterinarian treated the puppy with a synthetic hormone called vasopressin, which helped reduce the urination and improve the urine concentration. Over the next few weeks, the puppy's symptoms improved, and the treatment was eventually stopped.
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Abstract
OBJECTIVE: To describe a clinical case of transient central diabetes insipidus (CDI) occurring post cardiopulmonary arrest (CPA) in a dog. CASE SUMMARY: An 8-week-old dog presented for intensive care after successful resuscitation following CPA. The patient exhibited neurologic deficits at initial presentation and over the following days developed marked polyuria, isosthenuria, and low urine osmolality. Treatment with synthetic vasopressin resulted in a reduction in urine output, increase in urine specific gravity (>50%), and increase in urine osmolality, suggesting a diagnosis of partial CDI. Clinical signs resolved over the following weeks and treatment was discontinued. NEW OR UNIQUE INFORMATION PROVIDED: CPA has been described as a cause of ischemic injury to the pituitary gland resulting in CDI in people. To the authors' knowledge, this is the first report of a dog developing transient partial CDI following CPA and successful resuscitation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26473756/