Peer-reviewed veterinary case report
Young dog drinking and peeing a lot diagnosed with diabetes insipidus
By R.R. Ribeiro et al.·Published in Arquivo Brasileiro de Medicina Veterinária e Zootecnia·2025·View original on DOAJ →
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Original publication title: Central diabetes insipidus in a young dog - case report
- Species:
- dog
Plain-English summary
An 11-month-old spayed female mongrel was brought in for excessive urination and thirst, which are signs of diabetes insipidus. After various tests, including blood work and urinalysis, the vet found that the dog's urine was very dilute, indicating the condition. The dog was treated with a medication called desmopressin, initially given as eye drops. After increasing the dose, the dog's symptoms improved significantly, and her water intake decreased by more than half, indicating successful management of her condition.
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Abstract
ABSTRACT This work reports a case of an 11-month-old spayed, female mongrel with polyuria, polydipsia, polakiuria and nocturia. Serum biochemistry (alkaline phosphatase, ALT, urea, creatinine, GGT, globulins, triglycerides, cholesterol, total proteins), hemogram, urinalysis and abdominal ultrasound were requested. Blood exams were within the normal range and the urinalysis resulted in urine density of 1.009. Therefore, SDMA, bile acids, bilirubin (total and fractions), urinary protein: creatinine ratio, urinary GGT, Antinuclear Antibodies (ANA), and a new urinalysis were performed. All the measured parameters were within the normal range, except for the urine density of 1.010, suggesting Diabetes Insipidus. The 12-hour water deprivation test associated with desmopressin acetate revealed an increase in urine density to 1.028 and 1.029, one and two hours after administration of the medicine. Treatment was initiated with 3 drops of DDAVP daily in each eye, resulting in a slight improvement in clinical signs, and the dose was increased to 4 drops daily, resulting in the disappearance of the clinical signs and decreased the daily water intake by over 50%.
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Search related cases →Original publication on DOAJ: https://doi.org/10.1590/1678-4162-13310