Peer-reviewed veterinary case report
Dog with brain and kidney Bipolaris fungal infection causing
By Giri, D K et al.·Published in Veterinary pathology·2011·Department of Veterinary Pathobiology, United States·View original on PubMed →
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Original publication title: Cerebral and renal phaeohyphomycosis in a dog infected with Bipolaris species.
- Species:
- dog
Plain-English summary
A 5-year-old male mixed-breed dog was diagnosed with serious brain and kidney infections caused by a fungus called Bipolaris. The dog showed symptoms like neurological issues and kidney problems, which led to further testing. Advanced molecular tests confirmed the presence of the fungus in the brain. This case is significant as it is the first known instance of this type of fungal infection affecting a dog. Treatment details were not specified, but early diagnosis and targeted therapy are crucial for recovery in such cases.
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Abstract
Mycotic meningoencephalitis in dogs may manifest as a primary disease of the central nervous system or as a part of disseminated infection. Fungi belonging to the genus Bipolaris are saprophytic plant pathogens and can cause disease in humans. The authors report a case of Bipolaris infection in a dog with granulomatous meningoencephalitis, nephritis, and vasculitis. The clinical and histological features resembled those of the more common aspergillosis, thus warranting confirmation by molecular methods. Polymerase chain reaction and sequence analysis identified Bipolaris from the brain lesion, indicating its involvement in the disease. To the authors' knowledge, this is the first reported case of meningoencephalitis caused by this fungus in a domestic animal.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20574070/