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Peer-reviewed veterinary case report

Saliva changes in choline levels in dogs with parvovirus infection

By Kocatürk, Meriç et al.·Published in Research in veterinary science·2021·Department of Internal Medicine·View original on PubMed →

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Original publication title: Changes in choline and cholinesterase in saliva of dogs with parvovirus infection.

Species:
dog
Canine parvovirus (parvo)Dogs

Plain-English summary

A group of dogs with parvovirus infection had their saliva tested to see if certain substances could indicate how severe their illness was. The results showed that the level of choline in their saliva was higher compared to healthy puppies, and this increase was linked to higher levels of inflammation markers in their blood. While another substance, butyrylcholinesterase, did not show any significant changes, the findings suggest that measuring choline in saliva could help veterinarians assess how serious a dog's parvovirus infection is.

People also search for: dog parvovirus symptoms · choline levels in dog saliva · how to treat parvovirus in puppies

Abstract

This study investigated the changes in choline (Ch) and butyrylcholinesterase (BChE) in saliva in canine parvovirosis (CP) as a model of sepsis, and their correlations with these analytes in serum and with other markers of inflammation such as white blood cell count (WBC) and serum C-reactive protein (CRP). A total of 30 dogs with CP were sampled for saliva and serum at presentation, and 10 healthy puppies were also sampled as controls. Salivary Ch was higher in dogs with CP (P&#xa0;<&#xa0;0.001) showing a positive correlation with CRP, whereas no differences were observed in salivary BChE. This is the first report in which Ch is measured in saliva of dogs and based in the results of this study, salivary Ch could be potentially used as biomarker of the severity of CP.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33385977/

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