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Peer-reviewed veterinary case report

Changes in the lipid composition of blood plasma and liver in rats induced by severe psychic trauma.

Journal:
Bulletin of experimental biology and medicine
Year:
2006
Authors:
Tsikunov, S G et al.
Affiliation:
I. P. Pavlov Department of Physiology
Species:
rodent

Abstract

The concentration of high-density lipoprotein cholesterol and triglycerides in rat serum sharply decreased after psychic trauma caused by life hazard. The content of these substances remained unchanged for not less than 1 week after trauma. The concentration of high-density lipoprotein cholesterol was low, while serum content of triglycerides increased 6 weeks after trauma. The concentration of high-density lipoprotein cholesterol significantly decreased after repeated psychic trauma. These changes were accompanied by a sharp increase in the concentration of triglycerides in the serum. Total cholesterol concentration in the liver decreased under these conditions.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17181072/