Peer-reviewed veterinary case report
Lacrimal gland inflammation causing dry eye in dogs with leishmaniosis
By Naranjo, Carolina et al.·Published in Veterinary parasitology·2005·Departarnent de Medicina i Cirurgia Animals, Spain·View original on PubMed →
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Original publication title: Characterization of lacrimal gland lesions and possible pathogenic mechanisms of keratoconjunctivitis sicca in dogs with leishmaniosis.
- Species:
- dog
Plain-English summary
A study found that some dogs with leishmaniosis, a disease caused by a parasite, also developed keratoconjunctivitis sicca (KCS), which is a condition that leads to dry eyes. In these dogs, the researchers noticed inflammation around the glands that produce tears, which could be causing the eyes to not produce enough moisture. The inflammation was often linked to the presence of the parasite. This suggests that treating the underlying leishmaniosis may help manage the eye problems in affected dogs.
People also search for: dog dry eyes treatment · leishmaniosis in dogs symptoms · keratoconjunctivitis sicca causes in dogs
Abstract
In a previous study, it was found that 2.8% of dogs with leishmaniosis had keratoconjunctivitis sicca (KCS). The aim of this study was to characterize the lesions present in the lacrimal glands of dogs with leishmaniosis and to determine the presence of the parasite by means of immunohistochemistry. The inflammatory infiltrate was described as granulomatous or pyogranulomatous and was located around the ductal component of the glands. Immunoperoxidase staining localized the parasites following the same pattern. Samples from eyes that had clinical signs compatible with KCS presented inflammatory infiltrate and parasite more commonly than those from eyes without clinical signs. One of the mechanisms of KCS in dogs with leishmaniosis may be the inflammatory infiltrate located around the ducts of lacrimal glands, producing retrograde accumulation and retention of secretion. Meibomian gland was the most commonly affected by the infiltrate, highlighting the possibility of a qualitative KCS in these dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16023786/