Peer-reviewed veterinary case report
Calf with swollen lymph nodes diagnosed with juvenile B-cell lymphoma
By Harbo, Sam J et al.·Published in Veterinary clinical pathology·2004·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: Characterization of lymphocyte populations by flow cytometry in a calf with sporadic juvenile lymphoma.
- Species:
- cattle
Plain-English summary
A 2-month-old Angus heifer was brought to the vet because she had swollen lymph nodes and was not eating well. Blood tests showed a high number of unusual lymphocytes, which are a type of white blood cell, leading to a diagnosis of sporadic juvenile lymphoma, a type of cancer in young calves. Further tests on a lymph node confirmed that the cancer was of the B-cell type. Unfortunately, this condition indicates a serious health issue, and the prognosis for recovery can be poor in such cases.
People also search for: calf swollen lymph nodes · juvenile lymphoma in calves · calf not eating well treatment
Abstract
A 2-month-old Angus heifer was presented to Washington State University Veterinary Teaching Hospital for generalized peripheral lymphadenopathy and mild anorexia. Results of a CBC revealed marked lymphocytosis consisting primarily of large, atypical lymphocytes with cleaved, reniform nuclei. A presumptive diagnosis of sporadic juvenile lymphoma was made. To confirm these findings, a prescapular lymph node was submitted for histopathology, immunochemistry, and flow cytometric analysis. Peripheral blood also was analyzed by flow cytometry. Phenotypic characterization of lymph node and peripheral blood cell populations verified the calf had the B-cell form of sporadic juvenile lymphoma. The results of this investigation expand the phenotypic characterization of neoplastic lymphocytes in sporadic juvenile lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15334353/