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Peer-reviewed veterinary case report

Chronic active interstitial pancreatitis as a cause of transverse colonic obstruction and colic in a horse.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2015
Authors:
Lohmann, Katharina L & Allen, Andrew L
Affiliation:
Department of Large Animal Clinical Sciences (Lohmann) and Department of Veterinary Pathology (Allen) · Canada
Species:
horse

Plain-English summary

A mature Quarter horse was put to sleep after experiencing colic, which is severe abdominal pain, for three days. After the horse passed away, a thorough examination revealed that most of the large intestine was swollen, and the transverse colon was stuck to the pancreas, which showed signs of chronic active interstitial pancreatitis (a long-term inflammation of the pancreas). The horse also had other issues, including liver scarring, stomach inflammation, and changes in the adrenal glands. Unfortunately, the treatment options were not effective, leading to the decision to euthanize the horse.

Abstract

A mature Quarter horse was euthanized following colic of 3 days duration. Postmortem, the large intestine, except the descending colon, was diffusely distended and associated with adhesion of the transverse colon to the pancreas, which had changes consistent with chronic active interstitial pancreatitis. Other lesions included hepatic fibrosis, erosive gastritis, and bilateral adrenal cortical hyperplasia.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/26538675/