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Peer-reviewed veterinary case report

Chronic bronchopulmonary aspergillosis in a horse with Cushing's syndrome.

Journal:
Mycoses
Year:
1996
Authors:
Carrasco, L et al.
Affiliation:
Department of Anatomy and Comparative Pathology · Spain
Species:
horse

Plain-English summary

A horse with Cushing's syndrome, which is a condition that affects hormone levels, was diagnosed with a rare type of lung infection caused by a fungus called Aspergillus. This infection was unusual because of the way the fungus appeared and where it was located in the horse's lungs. The diagnosis was confirmed using special tests that involved antibodies to identify the specific type of fungus. The treatment details and outcome were not provided, so it's unclear how the horse responded to the diagnosis and any potential treatment.

Abstract

An atypical case of chronic equine bronchopulmonary aspergillosis with an unusual hyphal morphology was diagnosed in a horse with Cushing's syndrome. Because of the hyphal localization in chronic ectatic bronchi and bronchioles, and juxtabronchiolar processes, the observed type of aspergillosis is similar to 'saprophytic bronchopulmonary aspergillosis' or 'semi-invasive pulmonary aspergillosis' in humans. The aetiological diagnosis of aspergillosis was accomplished by the application of a panel of monospecific polyclonal and monoclonal antibodies in immunohistochemical techniques.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/9145001/