Peer-reviewed veterinary case report
Cat with chronic myelogenous leukemia and high white blood cells
By Mochizuki, Hiroyuki et al.·Published in Journal of feline medicine and surgery·2014·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: Chronic myelogenous leukaemia with persistent neutrophilia, eosinophilia and basophilia in a cat.
- Species:
- cat
Plain-English summary
A 7-year-old male domestic shorthair cat was diagnosed with chronic myelogenous leukemia after a blood test showed a very high white blood cell count. Initially, the cat showed no symptoms, so the vet decided to monitor him without treatment. Seven months later, the cat developed itchy skin lesions, which were treated successfully with oral prednisolone. Later, he was diagnosed with nasal lymphoma, which was treated with radiation therapy, leading to complete remission. Remarkably, the cat remained in good health over five years later, despite ongoing blood abnormalities.
People also search for: cat leukemia symptoms · itchy skin in cats treatment · cat nasal lymphoma radiation therapy
Abstract
Chronic myelogenous leukaemia was diagnosed in a 7-year-old male neutered domestic shorthair cat. Leukocytosis (74,900/µl)--mature neutrophilia, eosinophilia and basophilia--was observed. Bone marrow aspiration revealed hypercellularity with proliferation of cells of myeloid lineage. An underlying condition leading to leukocytosis was not identified. The severe leukocytosis did not respond to antibiotic therapy. Based on these findings, chronic myelogenous leukaemia was diagnosed. Because of the absence of clinical signs, the cat was monitored without treatment until 7 months after diagnosis, when it developed pruritic skin lesions. Pruritus was controlled with oral prednisolone. Forty-two months after diagnosis, the cat developed nasal lymphoma, which was treated with radiation therapy, resulting in complete remission. The cat was still in good physical condition 63 months after diagnosis, despite the persistence of marked neutrophilia, eosinophilia and basophilia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24108200/