Peer-reviewed veterinary case report
Dogs with T-zone lymphoma often have swollen lymph nodes and long
By Mizutani, Noriyuki et al.·Published in The Journal of veterinary medical science·2016·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: Clinical and histopathological evaluation of 16 dogs with T-zone lymphoma.
- Species:
- dog
Plain-English summary
Sixteen dogs with T-zone lymphoma (a type of cancer affecting lymph nodes) were evaluated for symptoms and treatment. All the dogs had swollen lymph nodes, and half of them also had a skin condition called demodicosis. The study found that the cancer generally progressed slowly, with many dogs living for about 938 days after diagnosis. For some dogs, a watchful waiting approach was taken, and most of those dogs remained alive at the end of the follow-up period. This suggests that while T-zone lymphoma can be serious, many dogs can still have a good quality of life for some time after diagnosis.
People also search for: dog lymphoma symptoms · T-zone lymphoma treatment · swollen lymph nodes in dogs · dog skin problems · dog cancer survival rates
Abstract
Clinical and histopathological characteristics of 16 dogs with nodal paracortical (T-zone) lymphoma (TZL) were evaluated. At initial examination, generalized lymphadenopathy was found in all dogs, and peripheral lymphocytosis was found in 10 of the 16 dogs. At initial diagnosis or during the disease course, 8 dogs (50%) were affected with demodicosis. Immunohistochemical analysis for CD3, CD20 and CD25 was performed for 6 dogs with TZL; the tumor cells were positive for CD3 and CD25 and negative for CD20. Median overall survival time was 938 days. A watchful waiting approach was adopted for 6 cases (38%), and 5 of the 6 dogs were still alive at the end of follow-up. The clinical course of TZL in dogs is generally indolent; however, many cases develop a variety of infectious and other neoplastic diseases after the diagnosis of TZL.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27098109/