Peer-reviewed veterinary case report
Mild diarrhea and depression in pups with canine parvovirus Glu-426
By Decaro, Nicola et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2005·Department of Animal Health and Well-being, Italy·View original on PubMed →
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Original publication title: Clinical and virological findings in pups naturally infected by canine parvovirus type 2 Glu-426 mutant.
- Species:
- dog
Plain-English summary
Six puppies from two litters were found to have a mild infection caused by a specific strain of canine parvovirus. The puppies showed symptoms like mucoid diarrhea lasting about 3.5 days and signs of depression for about 1.5 days, but they did not experience vomiting or severe diarrhea. Only two of the puppies had fever and loss of appetite. The virus was detected in their feces for varying durations, with the highest levels found around day 10. Fortunately, the infection was mild, and the puppies were monitored closely for recovery.
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Abstract
An outbreak of canine parvovirus type 2 infection caused by the Glu-426 mutant in 2 litters of pups is reported. The infected pups (n = 6) were monitored daily for evidence of clinical signs and hematological changes and for the evaluation of viral shedding in the feces. The disease induced by the Glu-426 mutant was mild in all the infected pups. Vomiting and hemorrhagic diarrhea were not observed; however, the pups developed mucoid diarrhea (3.5 median days), depression (1.5 median days), and relative leukopenia and lymphopenia (2.5 median days). Fever and loss of appetite were observed only in 2 pups. Virus was detected in the feces for 4.5, 6.5, and 46 median days by hemagglutination, virus isolation on cell cultures, and real-time polymerase chain reaction (PCR), respectively. By real-time PCR, the highest viral DNA titers were detected in the feces of both litters at day 10, reaching median values of more than 10(10) DNA copies/mg of feces.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15825493/