Peer-reviewed veterinary case report
Signs and survival in dogs with primary kidney lymphoma
By Taylor, A et al.·Published in The Journal of small animal practice·2019·Royal Veterinary College, United Kingdom·View original on PubMed →
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Original publication title: Clinical characteristics and outcome of dogs with presumed primary renal lymphoma.
- Species:
- dog
Plain-English summary
A group of 29 dogs with suspected primary kidney cancer (renal lymphoma) showed symptoms like tiredness and stomach issues. Most had elevated waste products in their blood and abnormal red blood cell counts. Ultrasound scans revealed swollen kidneys and other signs of disease. The dogs were treated with chemotherapy, but only about half showed any improvement, and the overall survival time was short, averaging just over 12 days. Unfortunately, this type of cancer has a poor outlook, with limited response to treatment.
People also search for: dog kidney cancer symptoms · lymphoma treatment for dogs · why is my dog lethargic and vomiting
Abstract
OBJECTIVES: To characterise the presentation, clinicopathologic data and outcome of 29 dogs with presumed primary renal lymphoma. MATERIALS AND METHODS: Retrospective analysis of medical records of dogs with suspected primary renal lymphoma from 11 institutions. RESULTS: All dogs were substage b, and lethargy and gastrointestinal signs were common presenting complaints, as were azotaemia (n=25; 86%) and erythrocytosis (n=15; 51%) on biochemical testing. Ultrasonography typically revealed bilateral renal lesions (n=23; 79%), renomegaly (n=22; 76%) and abdominal lymphadenopathy (n=14; 48%). Chemotherapy was the only treatment in 23 dogs, of which 11 responded, all considered partial responses. For all dogs the median progression-free survival and median overall survival times were 10 days (range: 1 to 126) and 12 days (range: 1 to 212), respectively, and for dogs that responded to chemotherapy 41 days (range: 10 to 126) and 47 days (range: 10 to 212), respectively. CLINICAL SIGNIFICANCE: Primary renal lymphoma in dogs appears to be associated with a poor prognosis and short-lived response to chemotherapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31364180/