Peer-reviewed veterinary case report
Signs and treatment of colorectal lymphoma in 31 dogs
By Desmas, I et al.·Published in Veterinary and comparative oncology·2017·Royal veterinary College, United Kingdom·View original on PubMed →
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Original publication title: Clinical presentation, treatment and outcome in 31 dogs with presumed primary colorectal lymphoma (2001-2013).
- Species:
- dog
Plain-English summary
A group of 31 dogs diagnosed with presumed primary colorectal lymphoma (a type of cancer affecting the colon) showed symptoms like blood in their stool. Most of these dogs received chemotherapy, and some also had surgery or radiation therapy. On average, the dogs lived significantly longer compared to other types of lymphoma, with many surviving over 1,800 days after treatment. Younger dogs tended to have better outcomes, and those with blood in their stool had longer periods without disease progression. Overall, the study suggests that dogs with this condition can have a good prognosis with appropriate treatment.
People also search for: dog blood in stool treatment · colorectal lymphoma in dogs · dog cancer survival rates · chemotherapy for dogs with lymphoma · dog cancer treatment options
Abstract
The objective of this multicentre retrospective study was to describe clinical presentation, treatment and outcome and to determine prognostic factors for dogs with presumed primary colorectal lymphoma (PCRL). A total of 31 dogs were included. The predominant features of PCRL were high grade (n = 18) and immunophenotype B (n = 24). Most dogs were substage b (n = 25) with higher prevalence of haematochezia (n = 20). One dog had surgery only. Thirty dogs received chemotherapy; amongst them 13 had surgery or radiotherapy. Progression free survival (PFS) was 1318 days and disease-related median survival time (MST) was 1845 days. Fourteen dogs were alive at the end of the study with a median follow-up time of 684 days (3-4678 days). Younger dogs had longer PFS (P = 0.031) and disease-related MST (P = 0.01). Presence of haematochezia corresponded with longer PFS (P = 0.02). Addition of local treatment to chemotherapy did not significantly improve the outcome (P = 0.584). Canine PCRL has considerably longer PFS and MST than other forms of non-Hodgkin's lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/27028211/