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Peer-reviewed veterinary case report

Survival and response in cats with nasal cancer after palliative

By Giuliano, Antonio & Dobson, Jane·Published in Journal of feline medicine and surgery·2020·Department of Veterinary Medicine, United Kingdom·View original on PubMed

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Original publication title: Clinical response and survival time of cats with carcinoma of the nasal cavity treated with palliative coarse fractionated radiotherapy.

Species:
cat

Plain-English summary

A group of 28 cats with nasal cavity cancer received a type of radiation therapy called coarse fractionated radiotherapy to help relieve their symptoms. Most of the cats showed improvement in their clinical signs, and on average, they lived for about 342 days after treatment. However, those with more advanced cancer and facial deformities had shorter survival times. The treatment was generally well-tolerated, with some cats experiencing mild side effects like hair loss. Overall, this therapy can be effective for managing nasal cancer in cats, especially if the disease is caught early.

People also search for: cat nasal cancer treatment · feline radiation therapy side effects · how long do cats live with nasal carcinoma

Abstract

OBJECTIVES: Carcinoma is the second most common tumour of the nasal cavity in cats. Few studies assessing the response and survival of cats with carcinoma of the nasal cavity treated with palliative coarse fractionated radiotherapy have been published. METHODS: Twenty-eight cats were diagnosed with histologically confirmed carcinoma of the nasal cavity. All patients treated with a coarse fractionated radiotherapy protocol were retrospectively reviewed. RESULTS: Improvement of the clinical signs were reported in 24 cases; median survival time (MST) was 342 days; and cats with Adams modified stage IV and facial deformity had a significantly reduced MST of 152 days ( = 0.0013) and 67 days ( = 0.0002), respectively. Severe radiotherapy-related clinical signs were not reported and alopecia and leukotrichia were the most common side effects reported in ten cases. CONCLUSIONS AND RELEVANCE: Coarse fractionated radiotherapy treatment for carcinoma of the nasal cavity in cats is effective in relieving clinical signs. Long survival times can be achieved, in particular in cases with a less advanced stage of the tumour.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31944168/