Peer-reviewed veterinary case report
Clostridium perfringens type A myonecrosis in a horse in Korea.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2003
- Authors:
- Choi, Yang-Kyu et al.
- Affiliation:
- Korea Research Institute of Bioscience and Biotechnology · South Korea
- Species:
- horse
Plain-English summary
A 13-year-old male thoroughbred horse in Korea was diagnosed with a serious condition called myonecrosis, which involves severe swelling and bleeding in the muscles of the right hip area. After the muscle issues improved, the horse developed a sudden problem with breathing. Tests showed that the lungs had significant bleeding and some inflammation. The cause of death was determined to be respiratory failure, likely due to toxins produced by a type of bacteria called Clostridium perfringens type A, which was found in both the muscle and lung tissues. Unfortunately, despite identifying the bacteria and testing for treatment options, the horse did not survive.
Abstract
Acute hemorrhagic myonecrosis accompanied by severe inter- and intrafascicular edema and hemorrhage of the right gluteal area was diagnosed in a 13-year-old male thoroughbred horse. Once the muscular and fascicular changes were subsided, the horse then developed acute respiratory problem. Histologically, the lung had diffuse severe hemorrhage with mild neutrophilic infiltration. The cause of death was acute respiratory failure that is believed to occur secondary to toxaemic event. Alpha and beta2 toxin secreting Clostiridum perfringens type A was isolated from the muscle and lung. The diagnosis was based on the light microscopic examination, bacterial toxinotyping and toxin genotyping from the muscular and pulmonary lesion. Also, susceptibility of the isolates to antimicrobial agents was determined.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/14665756/