Peer-reviewed veterinary case report
Commercialization of plant-based vaccines from research and development to manufacturing.
- Journal:
- Animal health research reviews
- Year:
- 2004
- Authors:
- Howard, John A
- Affiliation:
- Biotechnology Institute · United States
Abstract
The benefits of using plant-based oral vaccines are discussed. Transgenic maize expressing an antigen of transmissible gastroenteritis virus (TGEV) is reported as a model to demonstrate efficacy. Young pigs that were fed the TGEV corn orally were protected against challenge with virulent TGEV. Additional parameters important in providing a reliable and consistent supply of plant-based vaccines are discussed. Finally, vaccines developed in maize are evaluated for their potential to contaminate either the food supply or the environment.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15984332/