Peer-reviewed veterinary case report
Accuracy of point-of-care blood typing for DEA 1.1 in dogs compared
By Blois, Shauna L et al.·Published in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)·2013·Department of Clinical Studies, Canada·View original on PubMed →
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Original publication title: Comparison of a gel column blood typing method and a point-of-care cartridge for dog erythrocyte antigen 1.1.
- Species:
- dog
Plain-English summary
A study looked at two methods for testing dogs' blood types, specifically for a key blood factor called DEA 1.1, which is important before blood transfusions. The researchers compared a traditional gel column method with a quicker point-of-care cartridge method in a group of healthy dogs and those with various health issues, including immune-mediated hemolytic anemia (IMHA). They found that both methods agreed well for healthy dogs and those without immune issues, but there were some discrepancies in the IMHA group. This suggests that while the cartridge method is promising, more research is needed for dogs with certain blood conditions.
People also search for: dog blood type test · DEA 1.1 blood typing for dogs · IMHA in dogs treatment
Abstract
BACKGROUND: Blood typing for the presence of Dog Erythrocyte Antigen (DEA) 1.1 is recommended in all donor and recipient dogs prior to transfusion of blood products. The objective of this study was to determine if a point-of-care DEA 1.1 blood typing cartridge could be used in place of the gel column typing method. STUDY DESIGN: Detection of DEA 1.1 was performed using a laboratory-based gel column method and a point-of-care cartridge. A convenience sample of 30 healthy blood donors, 13 dogs with immune-mediated hemolytic anemia (IMHA) (3 of which had concurrent immune-mediated thrombocytopenia [IMT]), and 44 dogs with other diseases was included in the study. KEY FINDINGS: Agreement was observed between the tests for normal dogs and dogs with nonimmune-mediated disease in 74/74 cases. Two dogs in the IMHA group had indeterminate gel column blood typing results; 1 dog in this group had a negative gel column test result but a positive cartridge test result. SIGNIFICANCE: There was good agreement between the 2 methods for normal dogs and dogs with nonimmune-mediated disease. Blood typing methods in dogs with IMHA should be further investigated.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23648208/