Peer-reviewed veterinary case report
Comparison of antigenicity between recently isolated bovine rotaviruses A and vaccine strains by cross-neutralizing antibody tests and their significance for immunization.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2023
- Authors:
- Hasan, Md Amirul et al.
- Affiliation:
- Graduate School of Agriculture · Japan
Abstract
Three bovine rotaviruses A (RVAs) isolated from a cattle farm in Japan were serotyped by serum neutralization assay, as compared with the RVA strains contained in a vaccine used on the same farm. Antisera were prepared against the three isolates and the vaccine strains of bovine RVA. The results of cross-neutralization tests revealed that the RVA isolates from this farm differed somewhat in serotype. Collected plasma from calves for 6 weeks after colostrum ingestion showed that maternal antibodies acquired against all isolates gradually decreased, but antibodies toward one isolate increased by 6 weeks after the mentioned decreasing. These results suggest that rotavirus vaccines administered to cows should include all serotypes commonly found in calves with diarrhea.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/36596544/