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Peer-reviewed veterinary case report

Blood and spleen PCR tests compared for diagnosing Ehrlichia canis

By Harrus, Shimon et al.·Published in Antimicrobial agents and chemotherapy·2004·School of Veterinary Medicine·View original on PubMed

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Original publication title: Comparison of simultaneous splenic sample PCR with blood sample PCR for diagnosis and treatment of experimental Ehrlichia canis infection.

Species:
dog
Canine ehrlichiosisBreathing & coughDogs

Plain-English summary

A dog diagnosed with acute canine monocytic ehrlichiosis (CME) was treated with doxycycline for 16 days. This antibiotic helped the dog recover from the infection. The study found that testing blood samples was just as effective as testing splenic samples for diagnosing the disease early, but splenic tests were better for checking if the infection was gone. Overall, the doxycycline treatment was successful in clearing the infection.

People also search for: dog ehrlichiosis treatment · doxycycline for dog infection · how to diagnose canine monocytic ehrlichiosis

Abstract

This report presents evidence that dogs recover from acute canine monocytic ehrlichiosis (CME) after 16 days of doxycycline treatment (10 mg/kg of body weight every 24 h). Blood PCR was as valuable as splenic aspirate PCR for early diagnosis of acute CME. Splenic aspirate PCR was, however, superior to blood PCR for the evaluation of ehrlichial elimination.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15504892/