Peer-reviewed veterinary case report
Accuracy of two rapid antibody tests for canine leishmaniasis
By Athanasiou, Labrini V et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2014·Clinic of Medicine·View original on PubMed →
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Original publication title: Comparison of two commercial rapid in-clinic serological tests for detection of antibodies against Leishmania spp. in dogs.
- Species:
- dog
Plain-English summary
A group of dogs showing signs of leishmaniasis, a disease caused by the Leishmania parasite, were tested for antibodies using two different rapid tests. The tests, Snap Canine Leishmania Antibody Test and ImmunoRun Antibody Detection kit, were found to be highly accurate, with both showing excellent sensitivity and perfect specificity. This means they can quickly confirm whether a dog has been exposed to the parasite, allowing for prompt treatment. Both tests can be useful tools for veterinarians in diagnosing leishmaniasis in dogs.
People also search for: dog leishmaniasis symptoms · rapid test for dog leishmania · leishmania treatment for dogs
Abstract
Antibodies against Leishmania spp. are detected in most dogs with clinical signs of leishmaniasis due to Leishmania infantum. Accurate, rapid in-clinic serological tests may permit immediate confirmation of the diagnosis and implementation of therapeutic measures. The aim of the current study was to evaluate the diagnostic accuracy of 2 commercial, rapid in-clinic serological tests for the detection of anti-Leishmania antibodies in sera of dogs, the Snap Canine Leishmania Antibody Test kit (IDEXX Laboratories Inc., Westbrook, Maine) and the ImmunoRun Antibody Detection kit (Biogal Galed Labs, Kibbutz Galed, Israel), using indirect fluorescent antibody test (IFAT) as the reference method. A total of 109 sera collected from 65 seropositive and 44 seronegative dogs were used. The sensitivities of the Snap and ImmunoRun kits were 89.23% (95% confidence interval: 79.05-95.54%) and 86.15% (95% confidence interval: 75.33-93.45%), respectively, and the specificity of both tests was 100%. A good agreement between each of the rapid in-clinic serological tests and IFAT and between the 2 rapid in-clinic serological tests was witnessed. Both rapid in-clinic serological tests showed an adequate diagnostic accuracy and can be used for the fast detection of antibodies against L. infantum in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24569224/