Peer-reviewed veterinary case report
Differences in cats with inflammatory bowel disease and high
By S. Bailey et al.·Published in Journal of Small Animal Practice·2010·View original on Semantic Scholar →
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Original publication title: Comparisons between cats with normal and increased fPLI concentrations in cats diagnosed with inflammatory bowel disease.
- Species:
- cat
Plain-English summary
A group of 23 cats diagnosed with inflammatory bowel disease (IBD) had their blood tested for a specific enzyme related to pancreatic health. The study found that cats with higher levels of this enzyme (≥12.0 µg/l) often had lower levels of important proteins in their blood, which could indicate more severe health issues. However, there were no significant differences in age, liver enzyme levels, or treatment responses among the different groups of cats. This suggests that while high enzyme levels may be linked to certain deficiencies, they don't necessarily affect the overall treatment outcomes for IBD.
People also search for: cat inflammatory bowel disease symptoms · cat pancreatic enzyme levels · cat low protein treatment
Abstract
OBJECTIVES The aim of this study was to compare age, serum albumin and cobalamin concentrations, serum alanine amino transferase and alkaline phosphatase activities, feline inflammatory bowel disease clinical disease activity index, pancreatic ultrasound findings, intestinal histopathology scores, outcome, treatment and clinical response between cats diagnosed with inflammatory bowel disease with normal or increased serum feline pancreatic lipase immunoreactivity concentrations. METHODS Medical records for 23 cats diagnosed with inflammatory bowel disease and with serum feline pancreatic lipase immunoreactivity concentrations available were reviewed. Three groups were compared; cats with serum feline pancreatic lipase immunoreactivity concentrations 2·0 to 6·8 µg/l (group A), 6·9 to 11·9 µg/l (group B) and ≥12·0 µg/l (group C). RESULTS Sixteen of the 23 cats had increased serum feline pancreatic lipase immunoreactivity concentrations; 9 cats in group B and 7 cats in group C. The remaining seven cats were in group A. Cats with serum feline pancreatic lipase immunoreactivity concentrations ≥12·0 µg/l had significantly lower median serum albumin and cobalamin concentrations. No significant differences were identified between the three groups for age, serum alanine amino transferase and alkaline phosphatase activities, feline inflammatory bowel disease clinical disease activity index, pancreatic ultrasound findings, intestinal histopathology scores, clinical outcome, treatment or clinical response. CLINICAL SIGNIFICANCE Hypoalbuminaemia and hypocobalaminaemia were more frequently observed in cats with serum feline pancreatic lipase immunoreactivity concentrations ≥12·0 µg/l.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/21050218