Peer-reviewed veterinary case report
Cats with inflammatory bowel disease and high pancreatic lipase
By Bailey, S et al.·Published in The Journal of small animal practice·2010·Department of Veterinary Clinical Sciences·View original on PubMed →
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Original publication title: Comparisons between cats with normal and increased fPLI concentrations in cats diagnosed with inflammatory bowel disease.
- Species:
- cat
Plain-English summary
A group of 23 cats diagnosed with inflammatory bowel disease (IBD) were studied to see how their pancreatic enzyme levels affected their health. The cats were divided into three groups based on their serum pancreatic lipase levels, which is a marker for pancreatic health. It was found that cats with higher enzyme levels (12.0 µg/l or more) had lower levels of albumin and cobalamin, which are important proteins and vitamins in the body. However, there were no significant differences in age, liver enzyme levels, or treatment outcomes among the groups. This suggests that while high pancreatic lipase levels are linked to lower albumin and cobalamin, they do not necessarily affect the overall treatment response in cats with IBD.
People also search for: cat inflammatory bowel disease treatment · high pancreatic lipase in cats · low albumin levels in cats
Abstract
OBJECTIVES: The aim of this study was to compare age, serum albumin and cobalamin concentrations, serum alanine amino transferase and alkaline phosphatase activities, feline inflammatory bowel disease clinical disease activity index, pancreatic ultrasound findings, intestinal histopathology scores, outcome, treatment and clinical response between cats diagnosed with inflammatory bowel disease with normal or increased serum feline pancreatic lipase immunoreactivity concentrations. METHODS: Medical records for 23 cats diagnosed with inflammatory bowel disease and with serum feline pancreatic lipase immunoreactivity concentrations available were reviewed. Three groups were compared; cats with serum feline pancreatic lipase immunoreactivity concentrations 2·0 to 6·8 µg/l (group A), 6·9 to 11·9 µg/l (group B) and ≥12·0 µg/l (group C). RESULTS: Sixteen of the 23 cats had increased serum feline pancreatic lipase immunoreactivity concentrations; 9 cats in group B and 7 cats in group C. The remaining seven cats were in group A. Cats with serum feline pancreatic lipase immunoreactivity concentrations ≥12·0 µg/l had significantly lower median serum albumin and cobalamin concentrations. No significant differences were identified between the three groups for age, serum alanine amino transferase and alkaline phosphatase activities, feline inflammatory bowel disease clinical disease activity index, pancreatic ultrasound findings, intestinal histopathology scores, clinical outcome, treatment or clinical response. CLINICAL SIGNIFICANCE: Hypoalbuminaemia and hypocobalaminaemia were more frequently observed in cats with serum feline pancreatic lipase immunoreactivity concentrations ≥12·0 µg/l.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21050218/