Peer-reviewed veterinary case report
Two dogs harmed by errors in compounded seizure medicines
By McConkey, Sandra E et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2012·Atlantic Veterinary College, Canada·View original on PubMed →
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Original publication title: Compounding errors in 2 dogs receiving anticonvulsants.
- Species:
- dog
Plain-English summary
A 5-year-old dog had more frequent seizures after receiving a flavored phenobarbital solution that had gone bad before its expiration date. Another dog showed signs of high potassium levels and bromine toxicity due to a serious mistake in the concentration of potassium bromide, which was five times stronger than it should have been. Both dogs needed immediate veterinary attention to address these issues. After correcting the medication errors, the dogs were treated and their conditions improved.
People also search for: dog seizures treatment · phenobarbital side effects in dogs · potassium bromide overdose in dogs
Abstract
Two cases that involve drug compounding errors are described. One dog exhibited increased seizure activity due to a compounded, flavored phenobarbital solution that deteriorated before the expiration date provided by the compounder. The other dog developed clinical signs of hyperkalemia and bromine toxicity following a 5-fold compounding error in the concentration of potassium bromide (KBr).
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23024385/