Peer-reviewed veterinary case report
CT scan signs of lymphoma in dogs with spleen and liver involvement
By Jones, I D et al.·Published in The Journal of small animal practice·2017·Department of Veterinary Clinical Sciences, United Kingdom·View original on PubMed →
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Original publication title: Computed tomographic findings in 12 cases of canine multi-centric lymphoma with splenic and hepatic involvement.
- Species:
- dog
Plain-English summary
A group of 12 dogs diagnosed with multi-centric lymphoma (a type of cancer affecting the lymph nodes) underwent CT scans to check for issues in their spleen and liver. Most of the dogs had normal-looking spleens and livers on the scans, but some had nodules that were examined further. The findings suggested that while many dogs appeared healthy in these organs, fine needle aspiration (a procedure to collect samples) is recommended to get a clearer picture of the disease's extent. The study highlights the importance of imaging and sampling in managing this type of cancer in dogs.
People also search for: dog lymphoma symptoms · canine cancer CT scan · splenic nodules in dogs · liver nodules in dogs · multi-centric lymphoma treatment in dogs
Abstract
OBJECTIVES: To describe the CT findings in a population of dogs with multi-centric lymphoma that involved the spleen and liver. MATERIALS AND METHODS: Clinical records between January 2008 and June 2015 were reviewed. Thoracic and abdominal CT examinations of patients diagnosed with multi-centric lymphoma were evaluated by a board-certified radiologist. A diagnosis of multi-centric lymphoma with splenic and hepatic involvement was based upon cytological identification and immunophenotyping of neoplastic lymphocytes in cellular samples harvested from a peripheral lymph node, the spleen and the liver. RESULTS: Twelve dogs were included in this study, of which 11 had B-cell lymphoma; immunophenotyping was inconclusive in one dog. The spleen appeared normal in seven dogs and nodules were identified in five dogs. Splenic nodules were hypoattenuating in four of five dogs and isoattenuating in one of five. After contrast administration, three of five appeared hypoattenuating and two of five isoattenuating. The liver appeared normal in 10 dogs and hepatic nodules were identified in two dogs. All hepatic nodules were isoattenuating before contrast and hypoattenuating following contrast administration. CLINICAL SIGNIFICANCE: The CT appearance of the spleen and liver was normal in the majority of dogs with multi-centric lymphoma. Fine needle aspiration of the spleen and liver is recommended when using CT to stage dogs with multi-centric lymphoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28762504/