Peer-reviewed veterinary case report
CT and MRI show meningeal syndrome in leukemic cat with seizures
By Morozumi, M et al.·Published in The Journal of veterinary medical science·1993·Togasaki Animal Hospital, Japan·View original on PubMed →
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Original publication title: Computed tomography and magnetic resonance findings of meningeal syndrome in a leukemic cat.
- Species:
- cat
Plain-English summary
A 3-year-old Japanese domestic cat with lymphocytic leukemia experienced severe seizures during chemotherapy. After imaging tests, it was found that there were issues in the brain's protective layers due to the leukemia. A spinal tap confirmed that cancer cells had infiltrated the area, leading to a diagnosis of meningeal syndrome. The cat received a treatment called cytosine arabinoside, which helped improve its neurological symptoms. Unfortunately, further examination after the cat passed away confirmed the presence of leukemia in the affected areas.
People also search for: cat seizures during chemotherapy · meningeal syndrome in cats · leukemia treatment for cats · cat brain imaging results
Abstract
A 3-year-old Japanese domestic cat with a diagnosis of lymphocytic leukemia showed severe generalized seizures in the course of chemotherapy after leukemic condition was improved clinically. Computed tomography (CT) and magnetic resonance (MR) imaging of the brain were carried out. Both contrast procedures disclosed enhancements at the falx cerebri and the margin of cerebral cortex. Among these procedures contrast MR imaging demonstrated the lesion most clearly. Cytological examination of cerebrospinal fluid obtained by spinal puncture showed the infiltration of malignant cells and the diagnosis of meningeal syndrome associated with lymphocytic leukemia was defined. Intrathecal administration of cytosine arabinoside partially improved the neurologic dysfunction. Autopsy and histopathological examination confirmed the infiltration of leukemic cells in the areas of meningeal lesion demonstrated with contrast CT and MR imaging. Thus these imaging techniques, especially contrast MR imaging, are useful tools for rapid and precise diagnosis of meningeal syndrome.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8117801/