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Peer-reviewed veterinary case report

Concurrent cryptosporidium and coronavirus infections in an Arabian foal with combined immunodeficiency syndrome.

Journal:
The Veterinary record
Year:
1990
Authors:
Mair, T S et al.
Affiliation:
Department of Veterinary Medicine · United Kingdom
Species:
horse

Plain-English summary

This case involves an Arabian foal with combined immunodeficiency syndrome, a genetic condition that makes these horses very vulnerable to infections. The foal showed signs of both digestive and respiratory infections, which is common in these cases. Tests revealed that the foal had infections from coronavirus, which had not been reported before in this syndrome, as well as cryptosporidia, a type of parasite. There were also indications of an adenovirus infection based on tissue samples. Unfortunately, the foal's condition highlights the severe risks associated with this syndrome, and it is likely that the infections contributed to a poor outcome.

Abstract

Combined immunodeficiency syndrome is an inherited disorder of the Arabian breed of horses. Affected foals usually die of infectious disease within the first few months of life, and the respiratory tract is the commonest site of infection. This report describes the clinical and pathological features of a case which showed signs of alimentary and respiratory infections. Intestinal infection by coronavirus (not previously recorded in cases of the syndrome) and cryptosporidia was identified. Histopathological evidence also suggested the presence of an adenovirus infection.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/2156372/