Peer-reviewed veterinary case report
Immune-mediated anemia and low platelets in 21 dogs
By Goggs, R et al.·Published in The Veterinary record·2008·Department of Veterinary Clinical Sciences·View original on PubMed →
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Original publication title: Concurrent immune-mediated haemolytic anaemia and severe thrombocytopenia in 21 dogs.
- Species:
- dog
Plain-English summary
A 5-year-old Airedale Terrier was brought to the vet with symptoms of weakness and bleeding, diagnosed with immune-mediated hemolytic anemia (a condition where the body destroys its own red blood cells) and severe thrombocytopenia (low platelet count). The dog was treated with medications including glucocorticoids, vincristine, and azathioprine, but unfortunately, most of the dogs in the study did not survive long after treatment, with many passing away within a month. This condition can be serious, and early intervention is crucial for better outcomes.
People also search for: dog weakness and bleeding · Airedale Terrier immune-mediated hemolytic anemia treatment · dog low platelet count symptoms
Abstract
The medical records of 21 dogs with concurrent immune-mediated haemolytic anaemia (imha) and severe thrombocytopenia (defined as an automated platelet count of less than 50x10(9)/l, confirmed by the examination of a blood smear) were reviewed. Their mean (sd) age was 5.8 (2.5) years. When compared with the 24,759 dogs in the hospital population for the same period Airedale terriers and dobermanns appeared to be over-represented with odds ratios of 22.5 (95 per cent confidence interval [ci] 5.2 to 97.9) and 7.6 (95 per cent ci 1.8 to 32.7) respectively. The median duration of the dogs' clinical signs was seven days, with a range from one to 17 days. Eleven of the dogs had a history of a tendency to bleed, and 15 had evidence of bleeding when examined. Twenty of the 21 dogs had been treated with glucocorticoids, nine with vincristine, and seven with azathioprine. Their median stay in hospital was four days, with a range from one to 17 days. The median period for which they survived after admission to hospital was five days, with a range from one to 558 days, and 16 of the 21 dogs had died or been euthanased within 30 days of their admission.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18791206/