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Peer-reviewed veterinary case report

Dog with vomiting and bleeding diagnosed with two types of T-cell

By Suwa, Akihisa & Shimoda, Tetsuya·Published in The Journal of veterinary medical science·2017·Sanyo Animal Medical Center, Japan·View original on PubMed

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Original publication title: Concurrent with T-zone lymphoma and high-grade gastrointestinal cytotoxic T-cell lymphoma in a dog.

Species:
dog

Plain-English summary

A 9-year-old spayed female Golden Retriever was brought in for swollen lymph nodes and high white blood cell counts after showing signs of not eating, vomiting, and passing dark stools for two days. Tests revealed she had two types of lymphoma: T-zone lymphoma and high-grade gastrointestinal lymphoma. Despite starting chemotherapy, her condition worsened, and she sadly passed away just 15 days after her diagnosis.

People also search for: dog vomiting and not eating · Golden Retriever lymphoma treatment · dog lymph node swelling causes

Abstract

A 9-year-old, spayed female Golden Retriever dog was referred to us for lymphocytosis and lymphadenopathy, secondary to suspected chronic lymphocytic leukemia (CLL). The dog had a clinical history of anorexia, vomiting and melena lasting two days. The popliteal lymph node contained small-to-intermediate lymphocytes, which led us to suspect low-grade lymphoma. Thickened lesions in the stomach and small intestine were detected by ultrasonography. Histopathology of the popliteal lymph node and small intestine revealed a simultaneous presence of T-zone lymphoma (TZL) and high-grade gastrointestinal (GI) cytotoxic T-cell lymphoma. Large granular lymphocytes (LGLs) were seen on cytological examination. Polymerase chain reaction (PCR) revealed that both lymphomas originated in the T-cells. The dog died 15 days after diagnosis, despite chemotherapy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28302939/