Peer-reviewed veterinary case report
Condylomata acuminata.
- Journal:
- Journal of cutaneous pathology
- Year:
- 1976
- Authors:
- Vaughan, J T et al.
- Species:
- horse
Plain-English summary
A 5-year-old Thoroughbred chestnut mare had been showing multiple growths around her vulva and the area around her rear end for about a year. These growths looked like moist warts and were white, making them stand out against the normal skin color. The veterinarian treated the lesions with a topical solution that quickly made them shrink. A closer examination of the skin under a microscope showed changes in the skin cells and signs of inflammation, but the normal skin around the growths still had its usual color. Overall, the treatment worked well to reduce the lesions.
Abstract
A 5-year-old Thoroughbred chestnut mare was presented because of multiple lesions noticed for approximately one year over the vulva and ther perianal areas. Clinically, there were moist warts that stood out because of their whitish color which contrasted strikingly with the surrounding, normally pigmented, uninvolved skin (Fig. 1). Repeated topical applications of 20% podophyllin in 95% ethyl alcohol produced rapid involution. Histopathologically, marked acanthosis, numerous mitoses, prominently vacuolated epidermal cells and a chronic dermal inflammatory infiltrate were seen (Figs. 2, 3, and 4). Interestingly, melanin in the basal cell layer was not visible in the lesions, but was very apparent in the normal epidermis at the edges of the lesions. Thus the contrast between the affected and the non-affected skin was also strikingly microscopically (Fig. 2 arrows).
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/1018065/