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Peer-reviewed veterinary case report

Vulvar Complex Apocrine Carcinoma in a Horse (Equus caballus): A Case Report and Review of Literature.

Journal:
Journal of equine veterinary science
Year:
2023
Authors:
Kumbhani, Tapan R et al.
Affiliation:
Department of Veterinary Pathology · India
Species:
horse

Plain-English summary

A 6-year-old Marwari mare had a recurring growth on her vulva, which is the external part of the female reproductive system. The growth was surgically removed and examined under a microscope, where it showed abnormal cell growth. Special tests indicated that the tumor was a complex apocrine carcinoma, a type of cancer that originates from sweat glands. This case is significant because it is the first confirmed instance of this type of cancer in horses.

Abstract

A 6-year-old Marwari mare presented with recurrent vulvar growth. The growth was surgically excised, fixed and processed routinely. Microscopically, neoplasm showed proliferation of epithelial and myoepithelial cells with tubulopapillary pattern. On immunohistochemistry, myoepithelial cells showed strong immunoreactivity with smooth muscle actin alpha and p63. On basis of histopathology and immunohistochemistry, tumour was diagnosed as complex apocrine carcinoma. This case report describes first confirm vulvar complex apocrine carcinoma in equines.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/37086757/