Peer-reviewed veterinary case report
How well core-needle biopsy diagnoses lymphoma in dogs
By Silva do Nascimento, Juliana et al.·Published in Topics in companion animal medicine·2021·rsico Filho Veterinary Teaching Hospital (HUVET), Brazil·View original on PubMed →
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Original publication title: Core-Needle Biopsy Efficacy in Histopathology Diagnosis of Canine Multicentric Lymphoma.
- Species:
- dog
Plain-English summary
A group of 16 dogs with swollen lymph nodes were tested for lymphoma, a type of cancer that affects the lymphatic system. The veterinarians used a core-needle biopsy (a small tissue sample) to check for cancerous cells, and in 12 out of 14 dogs diagnosed with lymphoma, the biopsy results were positive. This method proved to be very effective, accurately identifying lymphoma in most cases. The study showed that core-needle biopsy can help veterinarians make a clear diagnosis and understand the type and severity of lymphoma in dogs.
People also search for: dog swollen lymph nodes lymphoma · canine lymphoma diagnosis · core-needle biopsy for dogs
Abstract
Core-needle biopsy (CNB) is now widely used to diagnose and classify human lymphoma. Few studies, however, have reported the use of CNB in veterinary medicine for dogs with suspected lymphoma. The present study evaluated the efficacy of CNB sample collection to diagnose canine multicentric lymphoma morphology. 16 dogs of varying breeds with generalized peripheral lymphadenopathy and cytopathologic features suggestive of lymphoma were enrolled in the study. CNB followed by lymphadenectomy of the left popliteal lymph node was performed. Both samples underwent histopathologic evaluation. Among the 16 dogs, 14 had lymphoma. CNB was positive for lymphoma in 12 (85.7%) of these 14 dogs. CNB analysis for diagnosing dogs with multicentric lymphoma exhibited a sensitivity of 86% and a specificity of 100%. CNB was effective in generalized lymphadenopathies toward achieving a differential diagnosis and microscopic evaluation of multicentric lymphoma in dogs, revealing essential features for morphologic classification, such as cell size, histopathologic type, and grade.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34260990/