Peer-reviewed veterinary case report
Corpus callosum and experimental stroke: studies in callosotomized rats and acallosal mice.
- Journal:
- Stroke
- Year:
- 2011
- Authors:
- Jin, Kunlin et al.
- Affiliation:
- Buck Institute for Research on Aging · United States
- Species:
- rodent
Abstract
BACKGROUND AND PURPOSE: Interhemispheric inhibition via the corpus callosum has been proposed as an exacerbating factor in outcome from stroke. METHODS: We measured infarct volume and behavioral outcome after middle cerebral artery occlusion in callosotomized rats and acallosal mice. RESULTS: Neither callosotomy in rats nor callosal agenesis in mice improved infarct volume or behavioral outcome after middle cerebral artery occlusion. CONCLUSIONS: These findings argue against a role for transcallosal projections in exacerbating focal cerebral ischemia.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21737800/