Peer-reviewed veterinary case report
Signs and blood tests linked to dog ehrlichiosis confirmed by PCR
By Carla Fredrichsen Moya-Araujo et al.·Published in Semina: Ciências Agrárias·2012
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Original publication title: Correlation of clinical and hematological with definitive diagnosis of canine ehrlichiosis by PCR<br>Correlação dos achados clínicos e hematológicos com diagnóstico definitivo de erliquiose canina por meio de PCR
- Species:
- dog
Plain-English summary
A group of 20 dogs suspected of having ehrlichiosis, an infectious disease spread by ticks, were evaluated at a veterinary hospital in Brazil. Many of these dogs showed symptoms like loss of appetite, swollen liver and spleen, lethargy, and nosebleeds. A blood test called PCR confirmed that 65% of the dogs had the disease, and most of these also had low platelet counts and anemia. The study found that using PCR along with clinical signs and blood tests can help veterinarians accurately diagnose ehrlichiosis in dogs.
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Abstract
The Ehrlichiosis is a worldwide diseases of great importance in a veterinary medicine is an important infectious diseases whose prevalence has increased significant in the last year in the Brazilian states. Due to the fact that this study was designed to correlate the findings hematological clinical signs and PCR, being the most sensitive. This study evaluated twenty dogs seen at veterinary hospital UNESP – Botucatu campus during the 03 from august to September 28 2009. Animal cited 65% were positive in the PCR test. Among the most prominent clinical findings 76.92% (10/13) with anorexia, 53.84% (7/13) with hepatoesplenomegaly, 46.15% (6/13) with apathy and 38.46% (5/13) epistaxis. The thirteen animals positive PCR 92.30% (12/13) showed thrombocytopenia (<150.000 platelets) e 61.53 (8/13) anemic (<5.50 x10). Thus, we conclude that the PCR was a good method for detection differential canine ehrlichiosis may be adopted together with the clinical and hematological findings for the accurate diagnosis of the disease.<p><p> A Erliquiose é uma doença cosmopolita de grande importância na clínica médica veterinária, sendo uma importante enfermidade infecciosa, cuja prevalência tem aumentado significantemente nos últimos anos nos estados brasileiros. Devido a esse fato, o presente trabalho teve o intuito de correlacionar os achados hematológicos, sinais clínicos e PCR, sendo este último o mais sensível. No trabalho foram avaliados 20 cães com suspeita de Erliquiose que foram atendidos no setor de Moléstias Infecciosas do Hospital Veterinário da UNESP – Campus Botucatu SP, durante oito semanas. Dos animais citados, 65,00% (13/20) foram positivos em exame da PCR, nestes os achados clínicos mais evidentes foram 76,92% (10/13) anorexia, 53,84% (7/13) hepatoesplenomegalia, 46,15% (6/13) apatia e 38,46% (5/13) epistaxes. Dos treze animais positivos na PCR 92,30% (12/13) apresentaram-se trombocitopênicos (<150.000 plaquetas) e 61,53% (8/13) anêmicos (<5.50 x106). Frente ao exposto, conclui-se que a técnica de PCR foi um bom método diferencial na detecção de Erliquiose canina podendo ser adotada, juntamente com os achados clínicos e hematológicos para o diagnóstico preciso da enfermidade em questão.
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