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Peer-reviewed veterinary case report

Cranial mediastinal liposarcoma in a horse.

Journal:
Veterinary pathology
Year:
2012
Authors:
Kondo, H et al.
Affiliation:
Department of Infectious Diseases and Pathology · United States
Species:
horse

Plain-English summary

A 23-year-old Anglo-Arabian mare was brought in because she was having trouble breathing and had swelling in her chest area. After she passed away, a thorough examination revealed a large, irregularly shaped mass in her chest, which was identified as a type of cancer called liposarcoma (a cancer that develops from fat tissue). The mass was made up of unusual cells that had clear spaces in them, which were visible under a microscope. Unfortunately, the mare did not survive due to this serious condition.

Abstract

A 23-year-old Anglo-Arabian mare was presented with tachypnea, dyspnea, and pitting edema of the ventral thoracic subcutis. On necropsy, a tan to red, friable, irregularly shaped mass (23 × 20 × 18 cm) occupied the cranial mediastinum. Histologically, the mass was classified as a liposarcoma and was composed of short interlacing bundles of spindle-shaped to irregularly rounded cells with discrete, variably sized, clear cytoplasmic vacuoles, which were stained with oil red O in frozen sections of formalin-fixed tissue.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22287648/