Peer-reviewed veterinary case report
Dog with kidney cryptococcal infection causing excessive urination
By Newman, Shelley J et al.·Published in Journal of the American Veterinary Medical Association·2003·Department of Pathology, United States·View original on PubMed →
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Original publication title: Cryptococcal pyelonephritis in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old male Golden Retriever was brought to the vet for excessive urination and thirst, along with progressive regurgitation. Despite initial tests showing no bacterial infection, the dog's condition worsened, leading to tremors and neurological issues. Sadly, after the dog passed away, a post-mortem examination revealed that he had cryptococcal pyelonephritis, a fungal infection affecting the kidneys, which caused the symptoms. This case highlights how a serious fungal infection can lead to significant health problems in dogs, including kidney issues and neurological symptoms.
People also search for: dog excessive urination and thirst · Golden Retriever regurgitation treatment · cryptococcal infection in dogs
Abstract
A 5-year-old castrated male Golden Retriever was evaluated for polyuria, polydipsia, and progressive regurgitation thought to be a result of bacterial pyelonephritis and megaesophagus. Bacteriologic culture of urine failed to yield clinically relevant growth, and results of a urine sediment examination were normal. With time, intention tremors and progressive neurologic dysfunction were also observed. At necropsy, a diagnosis of cryptococcal disease was confirmed histologically and immunohistochemically. Findings in the dog of this report were indicative of nephrogenic diabetes insipidus with polyuria and polydipsia caused by cryptococcal pyelonephritis. Neurologic manifestations of systemic cryptococcus infection included megaesophagus, esophageal hypomotility, and regurgitation attributed to localization of cryptococcal organisms in the brain stem in the region of the dorsal motor nucleus of the vagus nerve. To the authors' knowledge, this is the first report of polyuria secondary to cryptococcal pyelonephritis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12555981/