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Peer-reviewed veterinary case report

Cryptosporidium passes the bile acid test to survive.

Journal:
Trends in parasitology
Year:
2025
Authors:
Pardy, Ryan D et al.
Affiliation:
Centre Armand-Frappier Sant&#xe9 · Canada
Species:
rodent

Abstract

Cryptosporidium spp. are an important cause of diarrheal disease worldwide. However, pathogenesis can vary between and within parasite species. Huang et al. identified CpMRP1 as a transporter of the microbial metabolite deoxycholic acid and virulence factor that determines infection outcome in susceptible mice.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41015748/