Peer-reviewed veterinary case report
CT-MRI guided radiation treatment for dog face bone cancer
By Kwon, Nahyun et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2026·Department of Veterinary Medical Imaging, South Korea·View original on PubMed →
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Original publication title: CT-MRI Fusion for Radiation Treatment Planning and Serial Imaging of a Canine Maxillofacial Osteosarcoma.
- Species:
- dog
Plain-English summary
A 10-year-old poodle was diagnosed with a bone cancer in the jaw area and received radiation therapy to target the tumor precisely. The treatment involved delivering a specific dose of radiation over four sessions, guided by advanced imaging techniques that combined CT and MRI scans. After treatment, the poodle experienced some temporary swelling in the tumor area, which was later found to be a normal response rather than actual tumor growth. Over the following months, the tumor shrank significantly, and the bone structure began to heal and return to normal.
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Abstract
A 10-year-old poodle with left maxillofacial osteosarcoma received volumetric modulated arc therapy delivering 32 Gy in four fractions. Treatment planning was guided by computed tomography-magnetic resonance imaging (CT-MRI) fusion for precise target delineation near the globe. Serial CT and MRI up to 12 months after treatment showed transient enlargement of intratumoral cysts with fluid-fluid levels immediately after treatment, indicating pseudoprogression, followed by marked tumor regression. Progressive cortical remodeling and re-ossification restored normal bone contours. These findings present the value of multimodal imaging in radiotherapy planning and follow-up of head and neck tumors to distinguish pseudoprogression from tumor growth and identify postradiation bone regeneration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/42175601/