Peer-reviewed veterinary case report
Surgery and lymph node biopsy for oral melanoma in dogs
By Raleigh, Matthew L et al.·Published in Journal of veterinary dentistry·2021·Center for Veterinary Dentistry and Oral Surgery, United States·View original on PubMed →
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Original publication title: Curative Intent Surgery of Oral Malignant Melanoma and Regional Lymph Node Biopsy Assessment in 25 Dogs: 2006-2017.
- Species:
- dog
Plain-English summary
Twenty-five dogs with oral malignant melanoma (a type of mouth cancer) underwent surgery to remove the tumor and nearby lymph nodes. Most of these dogs had successful surgeries with no remaining cancer at the edges of the removed tissue, and many received additional treatments afterward. On average, these dogs lived about 11 months after their surgery. The findings suggest that complete removal of the tumor can lead to longer survival times, although some dogs did have cancer spread to their lymph nodes at the time of surgery.
People also search for: dog oral melanoma treatment · dog mouth cancer surgery · dog lymph node biopsy results
Abstract
Medical records were searched for dogs that had received curative intent surgery for oral malignant melanoma and ipsilateral excisional regional lymph node biopsy. Twenty-seven dogs were operated on and 25 dogs of these dogs met the inclusion criteria of signalment, post-excision margin status, presence of metastasis for each biopsied lymphocentrum, survival time post-excision, presence of recurrence or metastasis at follow-up or at death/euthanasia, location of the primary tumor, and any postoperative adjuvant treatment. These 25 dogs had complete tumor excision with tumor-free margins and 19 (76%) had postoperative adjuvant therapy. Median survival time after excision for the dogs in this study was 335.5 days. Results of this study support previous work that documents prolonged survival time following complete excision of oral malignant melanoma with tumor-free surgical margins in dogs. Additionally, 4 dogs (16%) had histologically confirmed regional lymph node metastasis at the time of definitive surgery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35014552/