Peer-reviewed veterinary case report
Dog with rare aggressive skin tumor under the jaw
By H.J. Kim et al.·Published in Veterinární Medicína·2015·College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea, CZ·View original on DOAJ →
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Original publication title: Cutaneous extrarenal rhabdoid tumor in a dog: a case report
- Species:
- dog
Plain-English summary
An 11-year-old male Maltese dog was brought to the vet with a noticeable lump under his jaw. After examining the mass, the vet found it was a rare type of tumor known as a rhabdoid tumor, which is aggressive and not commonly seen in dogs. The vet used special tests to confirm the diagnosis and understand the tumor's characteristics. While the prognosis for such tumors can be serious, the case highlights the importance of proper diagnosis and understanding of these rare tumors in dogs.
People also search for: dog lump under jaw · Maltese tumor diagnosis · rhabdoid tumor in dogs
Abstract
Rhabdoid tumours (RTs) are rare, highly aggressive tumours of undetermined origin in humans, and are sub-classified as renal/extrarenal RTs depending on location. The origins of extrarenal rhabdoid tumours are an enigma and neoplasms have rarely been reported in non-primate species. An 11-year-old male Maltese dog was presented with a submandibular mass. Histologically, the mass was composed of sheets of highly pleomorphic "rhabdoid" cells, further characterised by the presence of large epithelioid cells with globular/fibrillar paranuclear inclusions. Further immunohistochemical analysis revealed that the neoplastic cells were positive for vimentin and desmin similar to human tumours. In addition, ultrastructural analysis showed that the intracytoplasmic inclusions were mainly composed of whorled bundles of intermediate filaments. Our results suggest a useful diagnostic approach to cutaneous, extrarenal rhabdoid tumours in dogs and describe their characteristics.
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Search related cases →Original publication on DOAJ: https://doi.org/10.17221/7987-VETMED