Peer-reviewed veterinary case report
Skin cancer from sweat glands in an 18-year-old cat
By Machida, Yukino et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2011·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Cutaneous invasive micropapillary carcinoma of probable apocrine sweat gland origin in a cat.
- Species:
- cat
Plain-English summary
An 18-year-old female cat was diagnosed with a rare skin tumor called invasive micropapillary carcinoma, which likely originated from her sweat glands. The tumor was found on her cheek and had a unique honeycomb appearance under the microscope. Although the tumor was complex, it was identified based on specific cell markers. Unfortunately, the details of treatment and outcome are not provided, but this type of tumor can be serious and may require surgical intervention. It's important for pet owners to monitor any unusual growths on their pets and consult a veterinarian for evaluation.
People also search for: cat skin tumor treatment · why does my cat have a lump on her cheek · invasive micropapillary carcinoma in cats
Abstract
An invasive micropapillary carcinoma (IMC) occurred in the buccal skin of an 18-year-old female cat. Histologically, the tumor had a honeycomb pattern characterized by clusters of neoplastic epithelial cells that were surrounded by empty clear spaces and lined with fibrocollagenous stroma. On immunohistochemistry, the neoplastic cells were positive for cytokeratin (clone CAM5.2; pancytokeratin, clone AE1/AE3) and carcinoembryonic antigen (CEA) but negative for cytokeratin 14, vimentin, S100, smooth muscle actin, and p63. The CEA-positive staining reaction was present along the outermost rim of the neoplastic cell clusters consistent with an "inside-out" immunoreactivity pattern. Examination of the tumor cells by electron microscopy revealed microvilli on the outermost rim of neoplastic cells that were directed toward the surrounding vacant space. Based on histomorphological characteristics, the neoplasm was defined as an IMC of "pure-type." The location site and immunohistochemical features suggest the tumor was most likely derived from the apocrine sweat glands in the buccal skin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21908336/